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Rheumatology Advance Access originally published online on June 27, 2008
Rheumatology 2008 47(9):1263-1264; doi:10.1093/rheumatology/ken238
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

EDITORIALS

A view on the pathogenesis of osteoarthritis from the shoulders of giants

F. Birrell1 and N. K. Arden2

1Northumbria Healthcare NHS Foundation Trust, Newcastle Hospitals NHS Foundation Trust, Musculoskeletal Research Group, Newcastle University, Newcastle upon Tyne and 2MRC Epidemiology Resource Centre, University of Southampton, Southampton General Hospital, Southampton, UK

Correspondence to: F. Birrell, Northumbria Healthcare NHS Foundation Trust, Newcastle Hospitals NHS Foundation Trust, Musculoskeletal Research Group, Newcastle University, Newcastle upon Tyne, UK. E-mail: Fraser.Birrell@ncl.ac.uk

The first 10% of the full text of this article appears below.

OA is a common problem with high impact on patients and healthcare costs, accounting for 97% of the increasing number of joint replacements performed in England and Wales [1]: 137 000 hip and knee replacements in 2007 [2]. There is currently a considerable focus on the treatment of OA, including clinical guidelines on the care and management of adults with OA by the National Institute for Health and Clinical Excellence (NICE) [3], Osteoarthritis Research Society International (OARSI) and European League Against Rheumatism (EULAR) guidelines for hip and knee OA [4–6]. These guidelines list a number of treatments with modest benefit for pain and function and recommend that management should include a combination of non-pharmacological . . . [Full Text of this Article]

Hand OA

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Spondylosis

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