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Rheumatology Advance Access originally published online on May 16, 2003
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Rheumatology 2003; 42: 841-845
© 2003 British Society for Rheumatology

Validity of the Nottingham Health Profile in a Finnish out-patient population with rheumatoid arthritis

T. Uutela, M. Hakala1,2, and H. Kautiainen2

Department of Internal Medicine, Central Hospital of Lapland, Rovaniemi,
1 University of Oulu, Oulu and
2 Rheumatism Foundation Hospital, Heinola, Finland

Objective. To assess the quality of life of 122 rheumatoid arthritis (RA) patients using the Nottingham Health Profile (NHP), which is a generic quality-of-life instrument, and to compare the results with those of 99 healthy local control subjects.

Methods. Our patient group represented consecutive out-patients from a central hospital. The NHP contains 38 items, each with a weighted score, that assess subjective distress on six dimensions: mobility, pain, energy, sleep, emotional reactions and social isolation.

Results. The median (age-adjusted) NHP scores for mobility, pain and energy showed statistically highly significant differences (P < 0.001) between the RA patients and the control group, indicating a poorer quality of life among the RA patients on all these dimensions. These NHP dimensions were also closely related to patients' experience of their overall health status. The NHP scores for sleep, emotional reaction and social isolation did not differ between the patients and the controls.

Conclusion. The NHP, an instrument for assessing health-related quality of life, differentiated RA patients from local healthy individuals on the dimensions of mobility, energy and pain.

KEY WORDS: Nottingham Health Profile, Quality of life, Out-patients, Rheumatoid arthritis, Finland.

Correspondence to: M. Hakala, Rheumatism Foundation Hospital, FIN-18120 Heinola, Finland. E-mail: markku.hakala{at}reuma.fi


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